As I pulled the fragrant catfish out of the oven, memories of lively Louisiana dinners flooded my mind. This Cajun Baked Catfish recipe is my go-to for a taste of the South that feels like a warm embrace. Unlike its fried counterpart, this baked version is not only lighter but also packed with a delightful spice mix that dances on your palate. In just under 30 minutes, you’ll have a dish that’s perfect for a quick family meal or an elegant gathering with friends. Imagine serving this flaky fish with crisp veggies or a refreshing salad, while everyone raves about the flavors of the South. Are you ready to whip up a culinary delight that’s both comforting and exciting? Let’s dive in!

Why is Cajun Baked Catfish so special?
Healthier Twist: This dish offers a lighter alternative to traditional fried catfish without sacrificing flavor.
Easy Prep: With its quick preparation, you can enjoy a delicious meal in under 30 minutes—perfect for busy weeknights!
Flavor Explosion: The Cajun seasoning provides a bold, zesty punch that brings your taste buds to life.
Versatile Feast: Whether baked, wrapped in tortillas, or served as a sandwich with remoulade, its adaptability makes it a year-round favorite.
Crowd-Pleaser: Impress family and friends alike—this dish is sure to become a beloved go-to. If you’re craving something equally comforting, don’t miss out on my Creamy Cajun Chicken Pasta for another flavorful option!
Cajun Baked Catfish Ingredients
Let’s get ready to whip up some magic in the kitchen!
For the Catfish
• Catfish – A mild fish that pairs beautifully with Cajun spices; fresh or wild-caught is best for flavor.
For the Cajun Seasoning Blend
• Cajun Seasoning – This spice mix is essential; adjust the cayenne based on your heat preference.
• Garlic Powder – Adds depth and a savory aroma; a little goes a long way for flavor enhancement.
• Onion Powder – Provides a sweet, mild taste that complements the spices perfectly.
• Paprika – This brings both color and a subtle sweetness to your dish; smoked paprika can offer an extra layer of flavor.
• Black Pepper – Freshly ground black pepper enhances the spice blend and brightens up the overall taste.
For the sauce
• Lemon Juice – Freshly squeezed is ideal; it brightens the entire dish and balances the richness.
• Hot Sauce – A dash adds a little extra heat if desired; it’s totally optional but highly recommended for that Cajun kick.
For Baking
• Butter – Use for richness; dotting it on top of the fish gives it a deliciously crispy finish—but feel free to replace it with olive oil for a lighter touch.
• Oil for Greasing – Prevents sticking; a well-greased baking dish is crucial for achieving that perfect crust!
These Cajun Baked Catfish Ingredients offer a wealth of flavor for your meal. Whether you stick to the recipe or make substitutions, each bite will bring a comforting taste of Southern cooking to your dinner table!
Step‑by‑Step Instructions for Cajun Baked Catfish
Step 1: Preheat the Oven
Begin by preheating your oven to 400°F (200°C). This step is crucial to ensure your Cajun Baked Catfish cooks evenly and reaches that perfect flaky texture. As the oven heats, take a moment to gather your baking dish and grease it with a thin layer of oil or butter, ensuring it’s well-coated to prevent sticking.
Step 2: Prepare the Spice Mix
In a small bowl, combine your Cajun seasoning ingredients, including garlic powder, onion powder, paprika, and black pepper. Stir well until the spices are fully blended, creating a fragrant mix. This seasoning will infuse your catfish with bold flavors, so don’t hesitate to adjust the cayenne pepper for your desired spice level!
Step 3: Season the Catfish
Take your catfish fillets and pat them dry with a paper towel for optimal texture. Then, generously sprinkle the prepared Cajun seasoning over both sides of the fish. Squeeze fresh lemon juice on top and, if desired, drizzle a touch of hot sauce. Allow the seasoned catfish to marinate for 10-15 minutes, letting those flavors soak in.
Step 4: Arrange in the Baking Dish
Once marinated, carefully place the seasoned catfish fillets in the greased baking dish, ensuring they have enough space in between. Dot the tops of the fillets with small pieces of butter or drizzle them with olive oil to enhance the richness. This step helps achieve a crispy, golden finish as they bake in the oven.
Step 5: Bake to Perfection
Slide the baking dish into the preheated oven and bake your Cajun Baked Catfish for 15-18 minutes. Keep an eye on it, as the fish is done when it flakes easily with a fork and the edges are slightly crispy. The delightful aroma will fill your kitchen, hinting at the amazing meal coming your way!
Step 6: Serve and Savor
Once baked, carefully remove the catfish from the oven and let it rest for a couple of minutes. This allows the juices to settle, enhancing the flavors. Serve your Cajun Baked Catfish hot, paired with your favorite sides like roasted vegetables or coleslaw, and watch as everyone enjoys this Southern delight bursting with flavor!

Expert Tips for Cajun Baked Catfish
• Marination Magic: Allow the catfish to marinate with Cajun seasoning and lemon juice for 15 minutes to maximize flavor absorption and tenderness.
• Prepping Right: Ensure your catfish is fully thawed and patted dry to achieve the best flaky texture—this prevents excess moisture from affecting the cooking process.
• Crispy Outcome: For a delightful crispy crust, consider using a cast iron skillet. Preheat the skillet before adding your catfish for an extra crunch.
• Temperature Check: Keep an eye on the baking time; your Cajun Baked Catfish is perfectly done when it flakes effortlessly with a fork. Don’t overcook!
• Storing Leftovers: Preserve any leftovers in an airtight container in the refrigerator for up to 2-3 days. Gently reheat in an oven for the best taste experience!
How to Store and Freeze Cajun Baked Catfish
Fridge: Store leftover Cajun Baked Catfish in an airtight container in the refrigerator for up to 2-3 days to maintain its flavor and texture.
Freezer: If you need to freeze it, wrap the cooked catfish tightly in plastic wrap and then foil, or use a freezer-safe container. It can last for up to 2 months.
Reheating: For the best results, reheat frozen Cajun Baked Catfish in an oven at 350°F (175°C) for 15-20 minutes, or until warmed through, to preserve its crispiness.
Thawing: Always thaw frozen catfish in the refrigerator overnight before reheating to ensure even cooking and prevent texture loss.
Make Ahead Options
These Cajun Baked Catfish fillets are perfect for meal prep enthusiasts looking to save time during busy weeknights! You can season the catfish with the Cajun spice mix and lemon juice up to 24 hours in advance, then cover and refrigerate to allow the flavors to meld beautifully. Just be sure to pat the fish dry before seasoning to maintain its texture. When you’re ready to cook, simply place the marinated catfish in a greased baking dish, dot with butter, and bake in a preheated oven for 15-18 minutes. This way, you’ll enjoy flavorful Cajun Baked Catfish with minimal effort, making dinner a breeze!
Cajun Baked Catfish Variations
Feel free to get creative with this recipe; your taste buds are ready for exciting new flavors and textures!
- Fish Alternative: Swap catfish for redfish, tilapia, or cod for different flavor profiles and textures.
- Blackened Style: For a smokier version, blacken the catfish in a hot cast iron skillet instead of baking—it adds great depth!
- Creamy Topping: Add a drizzle of creamy garlic butter sauce before serving for an indulgent twist. It’s like a warm hug for your taste buds!
- Herb Infusion: Mix in fresh herbs like parsley or thyme into the Cajun seasoning for a refreshing boost—herbs can truly elevate the dish.
- Taco Time: Serve the baked catfish in warm tortillas with fresh avocado and a zesty slaw for a mouthwatering taco night.
- Flavored Oils: Use flavored oils like Cajun-infused or garlic-infused olive oil to add an extra layer of flavor while greasing the pan.
- Crispy Crunch: Top with panko breadcrumbs mixed with Cajun seasoning before baking to create a crunchy coating that your family will love.
- New Orleans Sandwich: Layer the catfish on a toasted baguette with remoulade and pickles for a delicious, New Orleans-inspired sandwich.
And if you’re in the mood for a flavorful pasta dish, don’t miss out on my Cajun Chicken Pasta for another taste of the South!
What to Serve with Cajun Baked Catfish
The perfect pairing of flavors and textures transforms your meal into a memorable dining experience.
-
Creamy Coleslaw: The cool, crunchy slaw balances the spiciness of the catfish while adding a refreshing element.
-
Garlic Roasted Vegetables: Tender vegetables with a crispy bite echo the Cajun spice, enhancing the dish’s overall bold flavor.
-
Cilantro Lime Rice: This zesty rice adds a vibrant layer to the meal, helping to soak up the delicious sauces.
-
Buttered Corn on the Cob: Sweet corn contrasts with the savory catfish, giving your plate a burst of sunshine and flavor.
Consider serving a light, refreshing salad with a citrus vinaigrette as well. It adds brightness, making every bite feel fresh and inviting.
-
Pineapple Upside-Down Cake: For dessert, this classic Southern treat brings delightful sweetness, wrapping up the meal with a nostalgic touch.
-
Sweet Tea: A glass of sweet tea is an essential accompaniment to any Southern meal, perfect for cooling off those spicy bites!

Cajun Baked Catfish Recipe FAQs
How do I select the best catfish?
Absolutely! For the best flavor, look for fresh or wild-caught catfish. Fresh catfish should have a mild ocean scent and firm, shiny flesh. Avoid any fillets with dark spots or a strong fishy smell—these are signs they’re not fresh. If you’re using frozen catfish, ensure it’s completely thawed before cooking, as this affects the texture.
What’s the best way to store leftovers?
Very simple! After you’ve enjoyed your Cajun Baked Catfish, place any leftovers in an airtight container. It should be refrigerated within two hours of baking and can be stored for up to 2-3 days for best quality. For optimal freshness, make sure to keep it well-sealed to prevent it from drying out!
Can I freeze Cajun Baked Catfish?
Certainly! To freeze, wrap the cooled catfish tightly in plastic wrap and then in aluminum foil to prevent freezer burn. You can also use a freezer-safe airtight container. It will stay fresh for up to 2 months. When you’re ready to eat, thaw it overnight in the refrigerator for even cooking!
What if my catfish is too dry after baking?
Don’t worry, it happens to the best of us! To ensure a moist result, first, make sure to avoid overcooking—catfish should flake easily but not be dry. If you do find that your baked catfish turned out dry, consider serving it with a drizzle of lemon butter sauce or a creamy remoulade on the side to enhance the flavor and moisture.
Are there any dietary considerations for Cajun Baked Catfish?
Absolutely! Cajun Baked Catfish is naturally gluten-free and packed with protein. If you’re concerned about allergies, double-check your Cajun seasoning for any hidden gluten sources. Always opt for fresh ingredients, particularly for those with allergies or dietary restrictions. And for your furry friends, remember, fish is safe but avoid seasoning or sauces, as they can be harmful to pets.

Cajun Baked Catfish: Quick, Zesty Flavor for Dinner Bliss
Ingredients
Equipment
Method
- Preheat your oven to 400°F (200°C) and grease your baking dish with oil or butter.
- Combine Cajun seasoning ingredients in a small bowl and stir until fully blended.
- Pat catfish dry and sprinkle the Cajun seasoning over both sides. Squeeze lemon juice on top and optionally drizzle with hot sauce. Let marinate for 10-15 minutes.
- Place seasoned catfish in the greased baking dish and dot with butter or drizzle with olive oil.
- Bake for 15-18 minutes, until fish flakes easily with a fork and edges are crispy.
- Let the catfish rest for a couple of minutes before serving with your favorite sides.

Leave a Reply